ACS Central Science (Dec 2018)
Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space
- Sara E. Kearney,
- Gergely Zahoránszky-Kőhalmi,
- Kyle R. Brimacombe,
- Mark J. Henderson,
- Caitlin Lynch,
- Tongan Zhao,
- Kanny K. Wan,
- Zina Itkin,
- Christopher Dillon,
- Min Shen,
- Dorian M. Cheff,
- Tobie D. Lee,
- Danielle Bougie,
- Ken Cheng,
- Nathan P. Coussens,
- Dorjbal Dorjsuren,
- Richard T. Eastman,
- Ruili Huang,
- Michael J. Iannotti,
- Surendra Karavadhi,
- Carleen Klumpp-Thomas,
- Jacob S. Roth,
- Srilatha Sakamuru,
- Wei Sun,
- Steven A. Titus,
- Adam Yasgar,
- Ya-Qin Zhang,
- Jinghua Zhao,
- Rodrigo B. Andrade,
- M. Kevin Brown,
- Noah Z. Burns,
- Jin K. Cha,
- Emily E. Mevers,
- Jon Clardy,
- Jason A. Clement,
- Peter A. Crooks,
- Gregory D. Cuny,
- Jake Ganor,
- Jesus Moreno,
- Lucas A. Morrill,
- Elias Picazo,
- Robert B. Susick,
- Neil K. Garg,
- Brian C. Goess,
- Robert B. Grossman,
- Chambers C. Hughes,
- Jeffrey N. Johnston,
- Madeleine M. Joullie,
- A. Douglas Kinghorn,
- David G.I. Kingston,
- Michael J. Krische,
- Ohyun Kwon,
- Thomas J. Maimone,
- Susruta Majumdar,
- Katherine N. Maloney,
- Enas Mohamed,
- Brian T. Murphy,
- Pavel Nagorny,
- David E. Olson,
- Larry E. Overman,
- Lauren E. Brown,
- John K. Snyder,
- John A. Porco,
- Fatima Rivas,
- Samir A. Ross,
- Richmond Sarpong,
- Indrajeet Sharma,
- Jared T. Shaw,
- Zhengren Xu,
- Ben Shen,
- Wei Shi,
- Corey R.J. Stephenson,
- Alyssa L. Verano,
- Derek S. Tan,
- Yi Tang,
- Richard E. Taylor,
- Regan J. Thomson,
- David A. Vosburg,
- Jimmy Wu,
- William M. Wuest,
- Armen Zakarian,
- Yufeng Zhang,
- Tianjing Ren,
- Zhong Zuo,
- James Inglese,
- Sam Michael,
- Anton Simeonov,
- Wei Zheng,
- Paul Shinn,
- Ajit Jadhav,
- Matthew B. Boxer,
- Matthew D. Hall,
- Menghang Xia,
- Rajarshi Guha,
- Jason M. Rohde
Affiliations
- Sara E. Kearney
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Gergely Zahoránszky-Kőhalmi
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Kyle R. Brimacombe
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Mark J. Henderson
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Caitlin Lynch
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Tongan Zhao
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Kanny K. Wan
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Zina Itkin
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Christopher Dillon
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Min Shen
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Dorian M. Cheff
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Tobie D. Lee
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Danielle Bougie
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Ken Cheng
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Nathan P. Coussens
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Dorjbal Dorjsuren
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Richard T. Eastman
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Ruili Huang
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Michael J. Iannotti
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Surendra Karavadhi
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Carleen Klumpp-Thomas
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Jacob S. Roth
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Srilatha Sakamuru
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Wei Sun
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Steven A. Titus
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Adam Yasgar
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Ya-Qin Zhang
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Jinghua Zhao
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Rodrigo B. Andrade
- Department of Chemistry, Temple University, Philadelphia, Pennsylvania, United States
- M. Kevin Brown
- Department of Chemistry, Indiana University, Bloomington, Indiana, United States
- Noah Z. Burns
- Department of Chemistry, Stanford University, Stanford, California, United States
- Jin K. Cha
- Department of Chemistry, Wayne State University, Detroit, Michigan, United States
- Emily E. Mevers
- Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States
- Jon Clardy
- Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States
- Jason A. Clement
- Natural Products Discovery Institute, Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States
- Peter A. Crooks
- University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States
- Gregory D. Cuny
- Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, United States
- Jake Ganor
- Diamond Age Corp., McKinney, Texas, United States
- Jesus Moreno
- Department of Chemistry and Biochemistry, UCLA, Los Angeles, California, United States
- Lucas A. Morrill
- Department of Chemistry and Biochemistry, UCLA, Los Angeles, California, United States
- Elias Picazo
- Department of Chemistry and Biochemistry, UCLA, Los Angeles, California, United States
- Robert B. Susick
- Department of Chemistry and Biochemistry, UCLA, Los Angeles, California, United States
- Neil K. Garg
- Department of Chemistry and Biochemistry, UCLA, Los Angeles, California, United States
- Brian C. Goess
- Department of Chemistry, Furman University, Greenville, South Carolina, United States
- Robert B. Grossman
- Department of Chemistry, University of Kentucky, Lexington, Kentucky, United States
- Chambers C. Hughes
- Scripps Institution of Oceanography, UCSD, La Jolla, California, United States
- Jeffrey N. Johnston
- Department of Chemistry, Vanderbilt University, Nashville, Tennessee, United States
- Madeleine M. Joullie
- Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, United States
- A. Douglas Kinghorn
- College of Pharmacy, The Ohio State University, Columbus, Ohio, United States
- David G.I. Kingston
- Department of Chemistry, Virginia Tech, Blacksburg, Virginia, United States
- Michael J. Krische
- Chemistry Department, The University of Texas at Austin, Austin, Texas, United States
- Ohyun Kwon
- Department of Chemistry and Biochemistry, UCLA, Los Angeles, California, United States
- Thomas J. Maimone
- Department of Chemistry, University of California Berkeley, Berkeley, California, United States
- Susruta Majumdar
- Department of Molecular Pharmacology and Neurology, Memorial Sloan Kettering Cancer Center, New York, New York, United States
- Katherine N. Maloney
- Department of Chemistry, Point Loma Nazarene University, San Diego, California, United States
- Enas Mohamed
- University of Mississippi School of Pharmacy, Jackson, Mississippi, United States
- Brian T. Murphy
- College of Pharmacy, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois, United States
- Pavel Nagorny
- Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States
- David E. Olson
- Department of Chemistry, University of California, Davis, California, United States
- Larry E. Overman
- Department of Chemistry, University of California, Irvine, Irvine, California, United States
- Lauren E. Brown
- Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, Massachusetts, United States
- John K. Snyder
- Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, Massachusetts, United States
- John A. Porco
- Department of Chemistry and Center for Molecular Discovery (BU-CMD), Boston University, Boston, Massachusetts, United States
- Fatima Rivas
- Department of Chemical Biology and Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States
- Samir A. Ross
- University of Mississippi School of Pharmacy, Jackson, Mississippi, United States
- Richmond Sarpong
- Department of Chemistry, University of California Berkeley, Berkeley, California, United States
- Indrajeet Sharma
- Department of Chemistry and Biochemistry, and Institute of Natural Products and Research Technologies, University of Oklahoma, Norman, Oklahoma, United States
- Jared T. Shaw
- Department of Chemistry, University of California, Davis, California, United States
- Zhengren Xu
- Department of Chemistry, Florida Campus, The Scripps Research Institute, Jupiter, Florida, United States
- Ben Shen
- Department of Chemistry, Florida Campus, The Scripps Research Institute, Jupiter, Florida, United States
- Wei Shi
- Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Arkansas, United States
- Corey R.J. Stephenson
- Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States
- Alyssa L. Verano
- Pharmacology Graduate Program, Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, United States
- Derek S. Tan
- Pharmacology Graduate Program, Weill Cornell Graduate School of Medical Sciences, Memorial Sloan Kettering Cancer Center, New York, New York, United States
- Yi Tang
- Department of Chemistry and Biochemistry, UCLA, Los Angeles, California, United States
- Richard E. Taylor
- Department of Chemistry and Biochemistry and the Warren Family Research Center for Drug Discovery and Development, University of Notre Dame, Notre Dame, Indiana, United States
- Regan J. Thomson
- Department of Chemistry, Northwestern University, Evanston, Illinois, United States
- David A. Vosburg
- Department of Chemistry, Harvey Mudd College, Claremont, California, United States
- Jimmy Wu
- Department of Chemistry, Dartmouth College, Hanover, New Hampshire, United States
- William M. Wuest
- Department of Chemistry, Emory University, Atlanta, Georgia, United States
- Armen Zakarian
- Santa Barbara Department of Chemistry and Biochemistry, University of California, Santa Barbara, California, United States
- Yufeng Zhang
- School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong SAR
- Tianjing Ren
- School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong SAR
- Zhong Zuo
- School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong SAR
- James Inglese
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Sam Michael
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Anton Simeonov
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Wei Zheng
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Paul Shinn
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Ajit Jadhav
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Matthew B. Boxer
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Matthew D. Hall
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Menghang Xia
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Rajarshi Guha
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- Jason M. Rohde
- National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States
- DOI
- https://doi.org/10.1021/acscentsci.8b00747
- Journal volume & issue
-
Vol. 4,
no. 12
pp. 1727 – 1741
Abstract
No abstracts available.
