Investigating the mechanism of Echovirus 30 cell invasion

Yucai Liang; Junbing Chen; Congcong Wang; Bowen Yu; Yong Zhang; Zhijun Liu

doi:10.3389/fmicb.2023.1174410

Frontiers in Microbiology (Jul 2023)

Investigating the mechanism of Echovirus 30 cell invasion

Yucai Liang,
Junbing Chen,
Congcong Wang,
Bowen Yu,
Yong Zhang,
Zhijun Liu

Affiliations

Yucai Liang: Department of Microbiology, Weifang Medical University, Weifang, China
Junbing Chen: Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Gastrointestinal Cancer Center, Peking University Cancer Hospital and Institute, Beijing, China
Congcong Wang: Department of Microbiology, Weifang Medical University, Weifang, China
Bowen Yu: Department of Immunology, Weifang Medical University, Weifang, China
Yong Zhang: National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
Zhijun Liu: Department of Microbiology, Weifang Medical University, Weifang, China

DOI: https://doi.org/10.3389/fmicb.2023.1174410
Journal volume & issue: Vol. 14

Abstract

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Viruses invade susceptible cells through a complex mechanism before injecting their genetic material into them. This causes direct damage to the host cell, as well as resulting in disease in the corresponding system. Echovirus type 30 (E30) is a member of the Enterovirus B group and has recently been reported to cause central nervous system (CNS) disorders, leading to viral encephalitis and viral meningitis in children. In this review, we aim to help in improving the understanding of the mechanisms of CNS diseases caused by E30 for the subsequent development of relevant drugs and vaccines.

Published in Frontiers in Microbiology

ISSN: 1664-302X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.frontiersin.org/journals/microbiology

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Abstract

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