Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review

Nebojsa Lekic; Boris Tadic; Vladimir Djordjevic; Dragan Basaric; Marjan Micev; Dragica Vucelic; Milica Mitrovic; Nikola Grubor

doi:10.3390/medicina58020184

Medicina (Jan 2022)

Splenectomy for Visceral Leishmaniasis Out of an Endemic Region: A Case Report and Literature Review

Nebojsa Lekic,
Boris Tadic,
Vladimir Djordjevic,
Dragan Basaric,
Marjan Micev,
Dragica Vucelic,
Milica Mitrovic,
Nikola Grubor

Affiliations

Nebojsa Lekic: Department for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, Serbia
Boris Tadic: Department for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, Serbia
Vladimir Djordjevic: Department for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, Serbia
Dragan Basaric: Department for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, Serbia
Marjan Micev: Department for Pathology, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, Serbia
Dragica Vucelic: Department of Transfusion Medicine, Faculty of Medicine, University of Belgrade, Koste Todorovica Street, No. 6, 11000 Belgrade, Serbia
Milica Mitrovic: Center for Radiology and Magnetic Resonance Imaging, University Clinical Centre of Serbia, Pasterova No. 2, 11000 Belgrade, Serbia
Nikola Grubor: Department for HBP Surgery, University Clinical Centre of Serbia, Clinic for Digestive Surgery, Koste Todorovica Street, No. 6, 11000 Belgrade, Serbia

DOI: https://doi.org/10.3390/medicina58020184
Journal volume & issue: Vol. 58, no. 2
p. 184

Abstract

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Visceral leishmaniasis (also known as kala-azar) is characterized by fever, weight loss, swelling of the spleen and liver, and pancytopenia. If it is not treated, the fatality rate in developing countries can be as high as 100% within 2 years. In a high risk situation for perioperative bleeding due to severe thrombocytopenia/coagulopathy, we present a rare challenge for urgent splenectomy in a patient with previously undiagnosed visceral leishmaniasis. A histologic examination of the spleen revealed a visceral leishmaniasis, and the patient was successfully treated with amphotericin B.

Published in Medicina

ISSN: 1010-660X (Print); 1648-9144 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: https://www.mdpi.com/journal/medicina

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