PLoS ONE (Jan 2023)

The menstrual cycle and the COVID-19 pandemic.

  • Anita Mitra,
  • Jan Y Verbakel,
  • Lorraine S Kasaven,
  • Menelaos Tzafetas,
  • Karen Grewal,
  • Benjamin Jones,
  • Phillip R Bennett,
  • Maria Kyrgiou,
  • Srdjan Saso

DOI
https://doi.org/10.1371/journal.pone.0290413
Journal volume & issue
Vol. 18, no. 10
p. e0290413

Abstract

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BackgroundThe impact of COVID-19 virus on menstrual cycles in unvaccinated women is limited.ObjectiveTo investigate the prevalence of changes to menstrual cycle characteristics, hormonal symptoms and lifestyle changes prior to and during the COVID-19 pandemic.MethodsA retrospective online cross-sectional survey completed by social media users between July 2020 to October 2020. Participants were living in the United Kingdom (UK), premenopausal status and, or over 18 years of age.Main outcome(s) and measures(s)The primary outcome was to assess changes to menstrual cycle characteristics during the pandemic following the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). Secondary outcomes included assessment of hormonal and lifestyle changes.Results15,611 social media users completed the survey. Of which, 75% of participants experienced a change in their menstrual cycle, with significantly greater proportions reporting irregular menstrual cycles (PConclusionThe COVID-19 pandemic resulted in considerable variation in menstrual cycle characteristics and hormonal symptoms. This appears to be related to societal and lifestyle changes resulting from the pandemic, rather than to the virus itself. We believe this may have an impact on the individual, as well as national economy, healthcare, and population levels, and therefore suggest this should be taken into consideration by governments, healthcare providers and employers when developing pandemic recovery plans.