The Differences in Biochemical Reactants in The Acute Phase/Stage and Sleep Quality Considering The Type of Vascular Accesss in Patients on Hemodialysis

Abstract

In patients on hemodialysis (HD ), there is a high prevalence of disturbed sleep quality caused by unknown causes. The study aimed to compare differences in the levels of biochemical reactants in the acute phase, creatinine, sociodemographic factors, alexithymia, and sleep quality in a group of HD patients considering the vascular approach, as well as to determine differences between HD patients with normal and low sleep quality and to determine predictive factors for sleep quality. The research included 79 HD patients of both sexes, aged from 33 to 87, treated at UHC Osijek, General hospital Vinkovci, and Outpatient clinic Županja. Laboratory tests have been made on the HD , and clinical and sociodemographic information was collected. The authors used the Croatian version of the Pittsburgh sleep quality questionnaire for Toronto alexithymia scale 26 and the Epworth scale for daily sleepiness. HD patients who are dialysed through central venous catheter have significantly lower levels of albumins (p=0.02 Mann-Whitney U test), creatinine (p=0.007 Mann-Whitney U test), and they remain on dialysis for a shorter period of time compared to the patients with arteriovenous fistule (p=0.002 Mann-Whitney U test). Patients who are longer on HD have a 1.395 times higher chance for lower sleep quality (OR = 1.395 95% CI 1.02 do 1.74). The only predictive factor for lower sleep quality in HD patients is the duration of HD treatment.

Keywords

• Alexithymia
• Hemodialysis
• Sleep quality
• Circulatory approach