Structure-based rational design of an enhanced fluorogen-activating protein for fluorogens based on GFP chromophore

Affiliations

Marina V. Goncharuk: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Nadezhda S. Baleeva: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Dmitry E. Nolde: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Alexey S. Gavrikov: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Alexey V. Mishin: Moscow Institute of Physics and Technology
Alexander S. Mishin: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Andrey Y. Sosorev: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Alexander S. Arseniev: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Sergey A. Goncharuk: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Valentin I. Borshchevskiy: Moscow Institute of Physics and Technology
Roman G. Efremov: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Konstantin S. Mineev: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Mikhail S. Baranov: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS

Abstract

Structural analyses guide the rational design of mutant fluorogen-activating proteins with enhanced fluorescence.