RUDN Journal of Medicine (Dec 2008)
The screening of the compounds with antiaggregation activity among benzimidazole and xantine
Abstract
Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. We have synthesized L-65, on active compound, that suppresses platelet aggregation and has an acetylsalicylate acid-like effect. The results obtained concerning the screening of bioactive substances are promising.