RUDN Journal of Medicine (Dec 2008)

The screening of the compounds with antiaggregation activity among benzimidazole and xantine

  • G A Timirkhanova,
  • А V Samorodov,
  • Ye E Klyen,
  • O Y Travnikov,
  • D A Enikeyev,
  • V А Katayev

Journal volume & issue
Vol. 0, no. 4
pp. 68 – 72

Abstract

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Antiaggregation activity of first synthesized benzimidazole and xantine derivatives has been studied. Differences in impact of the compounds on blood coagulability have been shown. We have synthesized L-65, on active compound, that suppresses platelet aggregation and has an acetylsalicylate acid-like effect. The results obtained concerning the screening of bioactive substances are promising.