Communications Biology (Dec 2020)

Radixin modulates the function of outer hair cell stereocilia

  • Sonal Prasad,
  • Barbara Vona,
  • Marta Diñeiro,
  • María Costales,
  • Rocío González-Aguado,
  • Ana Fontalba,
  • Clara Diego-Pérez,
  • Asli Subasioglu,
  • Guney Bademci,
  • Mustafa Tekin,
  • Rubén Cabanillas,
  • Juan Cadiñanos,
  • Anders Fridberger

DOI
https://doi.org/10.1038/s42003-020-01506-y
Journal volume & issue
Vol. 3, no. 1
pp. 1 – 15

Abstract

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Sonal Prasad et al. identify several mutations in the radixin (RDX) gene that are associated with early-life hearing loss. Using a guinea pig model, they propose that radixin helps convert sound into electrical signals in the mature inner ear.