Ameloblastoma: A clinicoradiographic and histopathologic correlation of 11 cases seen in Goa during 2008-2012

Abstract

Objectives: The purpose of this case series was to compare the clinical, radiographic, and histopathologic features of 11 cases of ameloblastoma that reported to the Goa Dental College and Hospital over a period of 4 years from January 2008 to December 2012. Study Design: Data with respect to the patients′ ages, sex, location of lesions, radiographic features, histopathologic features and surgical treatment and follow-up, was analyzed. Results: The mean age in males was 23.25 ± 6.99 years, while that in females was 43.43 ± 17.13 years. Seven (63.63%) of the 11 subjects were females, and four (36.36%) were males. 10 (90.9%) of the 11 ameloblastomas were located in the mandible. Swelling was noted in all 11 patients. 10 cases showed radiographic findings, while one case was a peripheral soft-tissue variant. Seven (70%) of the 10 tumors were multilocular with a well-demarcated corticated border, and three cases (30%) were unilocular. Two cases showed a soap-bubble appearance. Histologically, five cases were unicystic, four were multicystic, one was desmoplastic and one was a peripheral variant. Follow-up ranged from 12 to 34 months and there were no signs of recurrence in any of the patients. Conclusions: Ameloblastomas more commonly occur in females at an older age, as compared with males. Radiographic features that could help in diagnosing ameloblastomas include its predominant occurrence in the mandible, multilocular radiolucency with well-defined, corticated, scalloped margins, expansion of buccal and lingual cortical plates, root resorption and tooth displacement.

Keywords

• Ameloblastoma
• desmoplastic
• multilocular
• peripheral
• unilocular