Valproate-Induced Reversible Brain Atrophy and Cognitive Deterioration

Abstract

Pediatric neurologists at Dalhousie University, Halifax, Nova Scotia, report an 8-year-old boy with rapid cognitive decline after a year-long course of valproate in varying dosages for myoclonic and atypical absence seizures.

Keywords

• encephalopathy
• epileptic seizures
• neurodegenerative diseases