Nature Communications (May 2022)

Achieving low-power single-wavelength-pair nanoscopy with NIR-II continuous-wave laser for multi-chromatic probes

  • Xin Guo,
  • Rui Pu,
  • Zhimin Zhu,
  • Shuqian Qiao,
  • Yusen Liang,
  • Bingru Huang,
  • Haichun Liu,
  • Lucía Labrador-Páez,
  • Uliana Kostiv,
  • Pu Zhao,
  • Qiusheng Wu,
  • Jerker Widengren,
  • Qiuqiang Zhan

DOI
https://doi.org/10.1038/s41467-022-30114-z
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

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The authors introduce stimulated-emission induced excitation depletion (STExD) nanoscopy using a single pair of low-power, near-infrared, continue-wave lasers. Emission of multichromatic probes is inhibited by cascade amplified depletion in lanthanide upconversion systems induced by manipulating their common sensitizer.