CHIMIA (May 2023)

Evolution of Solid Processing Methods in Continuous Flow Technology: Reactive Extrusion

  • Jamie A. Leitch,
  • Paul Richardson,
  • Duncan L. Browne

DOI
https://doi.org/10.2533/chimia.2023.339
Journal volume & issue
Vol. 77, no. 5

Abstract

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The frustrations of precipitation, fouling and blockages of liquid-based flow reactors is familiar to all researchers that have worked with continuous flow equipment. There have been many innovative solutions to try and circumvent this issue. This short review will highlight the emerging technique of mechanochemistry and reactive extrusion as a continuous process that can directly work on solid (and liquid) materials and elicit chemical transformations.

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