Nigerian Postgraduate Medical Journal (Jan 2013)
Prostatic tumours among Nigerian males: A private practice experience in Benin-City, South-South, Nigeria
Abstract
Aims and objectives : To highlight the frequency and histological types of prostatic tumours seen in a private practice setting in Benin-City, South-South Nigeria. Materials and Methods : Haematoxylin and eosin stained-slides of prostatic biopsies diagnosed at the Ashamas Foundation Diagnostic Centre, Benin-City for 10 years were archived and studied. Histological request forms were analysed for clinical bio-data, type of biopsies and diagnosis. Results : A total of 908 prostatic tumours comprising of 468 open prostatectomies, 378 transurethral prostatectomies, 60 needle biopsies and 2 unspecified biopsy types were diagnosed. The peak age incidence of prostatic tumours was 60-69 years accounting for 37% of all prostatic tumours. Nodular prostatic hyperplasia (NPH) was the most common tumour accounting for 74.9%. Prostatic cancer was the second most common tumour accounting for 22.1% of all prostatic tumours. Six cases (1.3%) of incidental carcinoma were diagnosed out of the 680 cases of NPH. Transitional cell carcinoma and metastatic carcinoma constituted 0.2%, 0.1% of prostatic tumours respectively. In all, carcinosarcoma and fibrosarcoma accounted for 0.1% each of the prostatic tumours. High grade prostatic intraepithelial neoplasm accounted for 0.2% while 1.1% was inadequate for histopathological diagnosis. Conclusion: Nodular prostatic hyperplasia accounted for vast majority of all prostatic tumours in this study. However a significant percentage of prostatic adenocarcinoma was also encountered. Health education and population based screening modalities are advocated to reduce prostatic tumour morbidity and mortality in the Nigerian adult male population.
