Our Clinical and Surgical Treatment Results in Patients with Familial Adenomatous Polyposis Coli

Abstract

Purpose: Familial adenomatous polyposis coli (FAP) is characterized by multiple adenomatous polyps in the colorectal region. Surgical treatment is the most decisive factor in FAP patients, as the risk of colorectal cancer is inevitable. In this study, it was aimed to present the results of patients who underwent surgical treatment with the diagnosis of FAP and the experiences of our clinic to the literature. Materials and Methods: The files of patients who underwent surgery for FAP between 2011 and 2020 in our center were retrospectively reviewed. Patients with multiple data deficiencies were excluded. 30 patients were included in the study. The findings of the patients were recorded. Results: 13 (43%) of the patients were male, 17 (57%) were female. Total proctocolectomy (TPK) was performed in 17 (57%) of the patients, and TK was performed in 13 (43%) of them. 15 of the patients' colonoscopies included suspicion of malignancy. Eight of the colonoscopic biopsies of these patients were adenocarcinoma. Specimen pathology was adenocarcinoma in 20 (67%) of the patients. Complications were seen in 10 (33%) of the patients and mortality was seen in 1. Complications were more common in patients with TPK (60%). Conclusion: Although FAP mostly involves the colon, it may involve the upper gastro intestinal system. Although surgery is still the most important step of the treatment, the complication rates are substantial. The type of surgery to be performed should be decided according to the age of the patient, the prevalence of polyp and compliance with follow-up.

Keywords

• familial adenomatous polyposis
• cancer
• colectomy