Drug Design, Development and Therapy (Jun 2016)
Anti-dengue drug: viral polyprotein, a potential target
Abstract
Syed Uzair Mahmood, Maryam Mushtaq, Maryam Jamil Syed Sindh Medical College, Jinnah Sindh Medical University, Karachi, PakistanWe would like to add our views regarding the article “Identification of covalent active site inhibitors of dengue virus protease” by Koh-Stenta et al.1 The article suggests the development of a possible drug to combat dengue virus. The drug will inhibit the ability of the virus to replicate by inhibiting the protease enzyme of the virus.View original paper by Koh-Stenta and colleagues.
