Nature Communications (Jan 2023)

A population-based matched cohort study of major congenital anomalies following COVID-19 vaccination and SARS-CoV-2 infection

  • Clara Calvert,
  • Jade Carruthers,
  • Cheryl Denny,
  • Jack Donaghy,
  • Lisa E. M. Hopcroft,
  • Leanne Hopkins,
  • Anna Goulding,
  • Laura Lindsay,
  • Terry McLaughlin,
  • Emily Moore,
  • Bob Taylor,
  • Maria Loane,
  • Helen Dolk,
  • Joan Morris,
  • Bonnie Auyeung,
  • Krishnan Bhaskaran,
  • Cheryl L. Gibbons,
  • Srinivasa Vittal Katikireddi,
  • Maureen O’Leary,
  • David McAllister,
  • Ting Shi,
  • Colin R. Simpson,
  • Chris Robertson,
  • Aziz Sheikh,
  • Sarah J. Stock,
  • Rachael Wood

DOI
https://doi.org/10.1038/s41467-022-35771-8
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 11

Abstract

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The risks of major congenital anomalies associated with SARS-CoV-2 vaccination in early pregnancy are not well understood. Here, the authors conduct a population-based cohort study using electronic health records from Scotland and find no evidence of an association, supporting vaccine safety in pregnancy.