Nature Communications (Nov 2017)

Cell-permeable organic fluorescent probes for live-cell long-term super-resolution imaging reveal lysosome-mitochondrion interactions

  • Yubing Han,
  • Meihua Li,
  • Fengwu Qiu,
  • Meng Zhang,
  • Yu-Hui Zhang

DOI
https://doi.org/10.1038/s41467-017-01503-6
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 9

Abstract

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Studying interactions between lysosomes and mitochondria in living cells is difficult due to the limitations of existing probes. Here, the authors develop new cell-permeable fluorescent probes to image the dynamics of lysosomes and their physical interactions with mitochondria using super-resolution microscopy.