Einstein (São Paulo) ()

Sarcopenia and chemotherapy-mediated toxicity

  • Maria Cecília Monteiro Dela Vega,
  • Alessandro Laviano,
  • Gustavo Duarte Pimentel

DOI
https://doi.org/10.1590/s1679-45082016md3740
Journal volume & issue
Vol. 14, no. 4
pp. 580 – 584

Abstract

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ABSTRACT This narrative review focuses on the role of sarcopenia and chemotherapy-induced toxicity in cancer patients. Consistent evidence shows that sarcopenia in cancer patients leads to decreased overall survival by influencing treatment discontinuation and dose reduction. Therefore, sarcopenia should be considered a robust prognostic factor of negative outcome as well as a determinant of increased healthcare costs.

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