Nature Communications (Jul 2019)

FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science

  • Heike Sichtig,
  • Timothy Minogue,
  • Yi Yan,
  • Christopher Stefan,
  • Adrienne Hall,
  • Luke Tallon,
  • Lisa Sadzewicz,
  • Suvarna Nadendla,
  • William Klimke,
  • Eneida Hatcher,
  • Martin Shumway,
  • Dayanara Lebron Aldea,
  • Jonathan Allen,
  • Jeffrey Koehler,
  • Tom Slezak,
  • Stephen Lovell,
  • Randal Schoepp,
  • Uwe Scherf

DOI
https://doi.org/10.1038/s41467-019-11306-6
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

Read online

To be able to use infectious disease next generation sequencing as a diagnostic tool, appropriate reference datasets are required. Here, Sichtig et al. describe FDA-ARGOS, a reference database for high-quality microbial reference genomes, and demonstrate its utility on the example of two use cases.