Nature Communications (Jul 2019)
FDA-ARGOS is a database with public quality-controlled reference genomes for diagnostic use and regulatory science
- Heike Sichtig,
- Timothy Minogue,
- Yi Yan,
- Christopher Stefan,
- Adrienne Hall,
- Luke Tallon,
- Lisa Sadzewicz,
- Suvarna Nadendla,
- William Klimke,
- Eneida Hatcher,
- Martin Shumway,
- Dayanara Lebron Aldea,
- Jonathan Allen,
- Jeffrey Koehler,
- Tom Slezak,
- Stephen Lovell,
- Randal Schoepp,
- Uwe Scherf
Affiliations
- Heike Sichtig
- U.S. Food and Drug Administration
- Timothy Minogue
- U.S. Army Medical Research Institute of Infectious Diseases
- Yi Yan
- U.S. Food and Drug Administration
- Christopher Stefan
- U.S. Army Medical Research Institute of Infectious Diseases
- Adrienne Hall
- U.S. Army Medical Research Institute of Infectious Diseases
- Luke Tallon
- Institute for Genome Sciences at the University of Maryland
- Lisa Sadzewicz
- Institute for Genome Sciences at the University of Maryland
- Suvarna Nadendla
- Institute for Genome Sciences at the University of Maryland
- William Klimke
- National Center for Biotechnology Information, National Library of Medicine
- Eneida Hatcher
- National Center for Biotechnology Information, National Library of Medicine
- Martin Shumway
- National Center for Biotechnology Information, National Library of Medicine
- Dayanara Lebron Aldea
- Lawrence Livermore National Laboratory
- Jonathan Allen
- Lawrence Livermore National Laboratory
- Jeffrey Koehler
- U.S. Army Medical Research Institute of Infectious Diseases
- Tom Slezak
- Lawrence Livermore National Laboratory
- Stephen Lovell
- U.S. Food and Drug Administration
- Randal Schoepp
- U.S. Army Medical Research Institute of Infectious Diseases
- Uwe Scherf
- U.S. Food and Drug Administration
- DOI
- https://doi.org/10.1038/s41467-019-11306-6
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 13
Abstract
To be able to use infectious disease next generation sequencing as a diagnostic tool, appropriate reference datasets are required. Here, Sichtig et al. describe FDA-ARGOS, a reference database for high-quality microbial reference genomes, and demonstrate its utility on the example of two use cases.