Detection of Opisthorchis viverrini Infection among the ASEAN Population in Thailand Using a Verbal Screening Test and Fecal Concentrator Kit

Natthawut KAEWPITOON; Soraya KAEWPITOON; Thirayu MEERERKSOM; Siwawich CHAN-ARAN; Wararat SANGWALEE; Jun NORKAEW; Jirayu CHUATANAM; Jirawoot KUJAPAN; Natnapa PADCHASUWAN; Taweesak TONGTAWEE; Likit MATRAKOOL; Ryan LOYD; Parichart WAKKHUWATTHAPONG

Iranian Journal of Parasitology (Jun 2018)

Detection of Opisthorchis viverrini Infection among the ASEAN Population in Thailand Using a Verbal Screening Test and Fecal Concentrator Kit

Natthawut KAEWPITOON,
Soraya KAEWPITOON,
Thirayu MEERERKSOM,
Siwawich CHAN-ARAN,
Wararat SANGWALEE,
Jun NORKAEW,
Jirayu CHUATANAM,
Jirawoot KUJAPAN,
Natnapa PADCHASUWAN,
Taweesak TONGTAWEE,
Likit MATRAKOOL,
Ryan LOYD,
Parichart WAKKHUWATTHAPONG

Affiliations

Natthawut KAEWPITOON: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand
Soraya KAEWPITOON: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND School of Family Medicine and Community Medicine, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand
Thirayu MEERERKSOM: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Dept. of Business Computer, Faculty of Management Science, Nakhon Ratchasima Rajabhat University, Nakhon Ratchasima, Thailand
Siwawich CHAN-ARAN: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Dept. of Business Computer, Faculty of Management Science, Nakhon Ratchasima Rajabhat University, Nakhon Ratchasima, Thailand
Wararat SANGWALEE: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand
Jun NORKAEW: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand
Jirayu CHUATANAM: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Dept. of Public Health, Faculty of Public Health, Vongchavalitkul University, Nakhon Ratchasima, Thailand
Jirawoot KUJAPAN: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Dept. of Public Health, Faculty of Liberal Arts and Science, Roi-Et Rajabhat University, Roi-Et, Thailand
Natnapa PADCHASUWAN: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Dept. of Health Education, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand
Taweesak TONGTAWEE: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand
Likit MATRAKOOL: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand
Ryan LOYD: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND Suranaree University of Technology Hospital, Suranaree University of Technology, Nakhon Ratchasima, Thailand AND School of Family Medicine and Community Medicine, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand
Parichart WAKKHUWATTHAPONG: Parasitic Disease Research Center, School of Medicine, Suranaree University of Technology, Nakhon Ratchasima, Thailand

Journal volume & issue: Vol. 13, no. 2

Abstract

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Background: Opisthorchis viverrini is a serious health problem in Southeast Asia. The infection is associated with cholangiocarcinoma. Therefore, this study was aimed to detect O. viverrini infections among the ASEAN population in Thailand. Methods: A cross-sectional study was conducted among 249 individuals from ASEAN populations in Thailand including Thai, Laotian, Cambodian, and Myanmar. Participants were screened using the O. viverrini verbal screening test (OvVST). Fecal samples were processed by the mini-parasep sf parasite fecal concentrator. Results: The infection rate of O. viverrini was 27.21%. The majority of infections was detected in females, in the age group 31-40 yr old, in the primary school education level, and in the occupation of labor. By country, O. viverrini infection was detected more often in the Lao PDR (30.77%). In screening for O. viverrini infection, OvVST had a high sensitivity (93.48%), specificity (86.70%), NPV (98.32%), and accuracy (87.95%). The PPV was 61.43% for OvVTS. The observed agreement was substantial for OvVST (k-value = 0.64). Conclusion: O. viverrini infections are still detected in ASEAN countries therefore large scale active surveillance is required. OvVST had a high sensitivity, specificity, and accuracy for screening the risk groups for O. viverrini.

Published in Iranian Journal of Parasitology

ISSN: 1735-7020 (Print); 2008-238X (Online)
Publisher: Tehran University of Medical Sciences
Country of publisher: Iran, Islamic Republic of
LCC subjects: Medicine: Internal medicine: Infectious and parasitic diseases
Website: http://ijpa.tums.ac.ir

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