PREGNANCY WITH INTRAUTERINE INSEMINATION AND OVULATION STIMULATION WITH CLOMIPHENE CITRATE

Abstract

Background. The aim of our study was to asses the success of the method of intrauterine insemination (IUI) and ovulation stimulation with clomiphene citrat compared to other techniques of assisted reproductive technology (AR).Methods. In retrograde, 533 cycles of IUI were analysed in 204 infertile couples. The success of IUI was compared according to the most common indications, the patients age and the successive cycle of IUI. The different values of the variables were compared using Pearson’s Chi-square test.Results. The overall pregnancy rate was 6.7%. The success was 2.35% in couples with a tubal cause of infertility (with one side tubal pathology), 12.12% in couples with male infertility only and 7.33% in couples with idiopathic infertility. The differences in the results of IUI between the age groups of female patients were not statistically significant.Conclusions. IUI is painless, noninvasive and less expensive method of AR and has therefore an important role for the treatment of infertility. IUI is suitable mainly for idiopathic infertility, some forms of male infertility and oligo – anovulations and if there are no contraindications we recommend it as treatment before IVF program.

Keywords

• intrauterine insemination
• clomiphene citrate
• success