Acta Medica Iranica (Mar 2003)

"Transformation of chronic myelogenous leukemia to Multiple Myeloma: A case report "

  • "Ghavamzadeh A,
  • Alimoghaddam K,
  • Mehdipour P,
  • Sharifian R,
  • Schwanitz G,
  • Shamshiri AR "

Journal volume & issue
Vol. 41, no. 1

Abstract

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Chronic myelogenous leukemia (CML) is a stem cell disorder sometimes associated with lymphoproliferative disorders. CML may precede a lymphoproliferative disorder. There are a few reports showing associating of CML with multiple myeloma and we report a known CML case that transformed into a full-blown multiple myeloma. This patient had more than 69% of infiltrating myeloma cells in her bone marrow and Philadelphia chromosome was detected in 18 out of 42. However, the probable presence of some myeloma cells with classic Philadelphia-positive chromosome could be proposed.

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