Vitamin D and the Metabolic Syndrome in Indian Sub-population

Abstract

Introduction: Low serum 5-hydroxyvitamin D [25(OH)D] levels have been related to insulin resistance, the metabolic syndrome (MetS) and its components. The aim of our analysis was to investigate the association of 25(OH)D with IDF-defined MetS. Design: This was a cross-sectional study of 50 participants aged 15–65 years. Results: Mean age of the participants was 42.14 years. 25(OH)D levels were inversely associated with BMI, waist circumference, systolic and diastolic blood pressure (BP), triglycerides, and fasting blood glucose (P<0.05). The percentage of subjects with MetS decreased across increasing quintiles of 25(OH)D (P<0.001). Conclusions: Our results demonstrate an inverse relationship between 25(OH)D levels and MetS in the Indian sub-population studied. Further investigations are required to clarify the clinical significance of these findings.

Keywords

• metabolic syndrome
• vitamin d
• body mass index
• blood glucose
• lipids
• ldl
• triglycerides
• waist circumference
• blood pressure