Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages

Wei Feng; Abha Bais; Haoting He; Cassandra Rios; Shan Jiang; Juan Xu; Cindy Chang; Dennis Kostka; Guang Li

doi:10.1038/s41467-022-35691-7

Nature Communications (Dec 2022)

Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages

Wei Feng,
Abha Bais,
Haoting He,
Cassandra Rios,
Shan Jiang,
Juan Xu,
Cindy Chang,
Dennis Kostka,
Guang Li

Affiliations

Wei Feng: Department of Developmental Biology, University of Pittsburgh School of Medicine
Abha Bais: Department of Developmental Biology, University of Pittsburgh School of Medicine
Haoting He: Department of Developmental Biology, University of Pittsburgh School of Medicine
Cassandra Rios: Department of Developmental Biology, University of Pittsburgh School of Medicine
Shan Jiang: Department of Developmental Biology, University of Pittsburgh School of Medicine
Juan Xu: Department of Developmental Biology, University of Pittsburgh School of Medicine
Cindy Chang: Department of Developmental Biology, University of Pittsburgh School of Medicine
Dennis Kostka: Department of Developmental Biology, University of Pittsburgh School of Medicine
Guang Li: Department of Developmental Biology, University of Pittsburgh School of Medicine

DOI: https://doi.org/10.1038/s41467-022-35691-7
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 19

Abstract

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A detailed multi-staged single cell atlas of heart development could improve our understanding of cell type diversification during cardiac development. Here, the authors generated a large dataset with cells from embryonic and neonatal hearts to identify the stage and chamber specific features in heart development.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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