Histomorphological Pattern of Analysis of Skin Adnexal Tumours- A Retrospective Study

Abstract

Introduction: Skin adnexal tumours are relatively uncommon in routine practice. They pose a diagnostic challenge to pathologists, due to their overlapping features and multiple lines of differentiation. Morphological assessment is crucial to subtype these lesions accurately. Aim: To study skin adnexal tumours based on their histomorphology and clinical profile. Materials and Methods: This was a retrospective, descriptive study conducted from January 2016 to December 2019 on 52 cases, done at BGS Global Institute of Medical Sciences, Bengaluru, Karnataka, India. All benign and malignant skin adnexal tumours were included in the study. Microscopic findings were studied by two pathologists. Based on histomorphological analysis, tumours were classified as per recent World Health Organisation (WHO) guidelines. Results: A total of 52 cases were studied. Of the 52 cases, 45 (87%) cases were benign and 7 (13%) cases were malignant. The most common benign adnexal tumour was Pilomatricoma and the most common malignant tumour was Sebaceous Carcinoma. The most common site of presentation was the head and neck, followed by lower limb and trunk. Conclusion: Skin adnexal tumours are subtyped based on the predominant morphological component. Benign adnexal tumours are more common compared to malignant adnexal tumours. Histopathological assessment is the mainstay in evaluating skin adnexal tumours.

Keywords

• appendageal neoplasms
• cylindroma
• histopathology
• nodular hidradenoma
• pilomatricoma