Seizures in HIV: The case for special consideration

Lilia Zaporojan; Patricia H. McNamara; Jennifer A. Williams; Colm Bergin; Janice Redmond; Colin P. Doherty

Epilepsy and Behavior Case Reports (Jan 2018)

Seizures in HIV: The case for special consideration

Lilia Zaporojan,
Patricia H. McNamara,
Jennifer A. Williams,
Colm Bergin,
Janice Redmond,
Colin P. Doherty

Affiliations

Lilia Zaporojan: Department of Neurology, St. James's Hospital, James's Street, Dublin 8, Ireland; Academic Unit of Neurology, Trinity Biomedical Science Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland; Corresponding author at: Department of Neurology, St. James's Hospital, James's Street, Dublin 8, Ireland.
Patricia H. McNamara: Department of Neurology, St. James's Hospital, James's Street, Dublin 8, Ireland; Academic Unit of Neurology, Trinity Biomedical Science Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland
Jennifer A. Williams: Department of Neurology, St. James's Hospital, James's Street, Dublin 8, Ireland; Academic Unit of Neurology, Trinity Biomedical Science Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland
Colm Bergin: Department of Infectious Diseases, St. James's Hospital, James's Street, Dublin 8, Ireland
Janice Redmond: Department of Neurology, St. James's Hospital, James's Street, Dublin 8, Ireland
Colin P. Doherty: Department of Neurology, St. James's Hospital, James's Street, Dublin 8, Ireland; Academic Unit of Neurology, Trinity Biomedical Science Institute, Trinity College Dublin, 152-160 Pearse Street, Dublin 2, Ireland

Journal volume & issue: Vol. 10
pp. 38 – 43

Abstract

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Purpose: This study aimed to determine the rate, cause and management of seizures in the context of potential ART–ASD interactions in a cohort of HIV+ individuals. Methods: Records of 604 HIV+ patients were reviewed and those reporting epilepsy/seizure diagnosis were further evaluated. Results: This cohort exhibited a seizure rate of 2.4%. HIV+ patients treated for epilepsy displayed low serum ASD levels and failed to achieve seizure control. They were more likely to disengage from Neurology follow-up. Conclusion: For HIV+ patients presenting with seizures/epilepsy the ASD prescription and the provision of supplementary support services needs to be carefully considered. Keywords: HIV, Seizure, Epilepsy, ASD–ART interaction

Published in Epilepsy and Behavior Case Reports

ISSN: 2213-3232 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry
Website: http://www.journals.elsevier.com/epilepsy-and-behavior-case-reports/

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