Chemokine Receptor 5 Δ32 Allele in Patients with Severe Pandemic (H1N1) 2009

Abstract

Because chemokine receptor 5 (CCR5) may have a role in pulmonary immune response, we explored whether patients with severe pandemic (H1N1) 2009 were more likely to carry the CCR5Δ32 allele than were members of the general population. We found a large proportion of heterozygosity for the CCR5Δ32 allele among white patients with severe disease.

Keywords

• Influenza
• CCR5
• pandemic (H1N1) 2009
• viruses
• dispatch
• Canada