Annals of Hepatology (Sep 2021)

P-64 THE ALCOHOL-ASSOCIATED LIVER DISEASE PARADOX IN CHILE: AN ASSESSMENT WITH DATA FROM THE NATIONAL HEALTH SURVEY (ENS 2016-2017)

  • Gianfranco Oneto,
  • Luis Antonio Díaz,
  • Francisco Idalsoaga,
  • Juan Pablo Arab,
  • Pablo Roblero,
  • Maximo Cattaneo,
  • Alvaro Urzua,
  • Jaime Poniachik,
  • Juan Pablo Roblero

Journal volume & issue
Vol. 24
p. 100427

Abstract

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Introduction: It has been observed people with low-income-level (IL). The aim of this study was to evaluate alcohol-associated liver disease (ALD) paradox in Chile. Methods: With data from the ENS 2016-17 (N=2,190; age 25-64) we constructed a logit regression model that estimated the effect hazardous AC (AUDIT≥8) on the probability of presenting ALD (GPT≥40 U/L). We focus on the interaction between hazardous AC and IL, controlling for the presence of metabolic syndrome (MS), diabetes mellitus (T2DM), obesity and tobacco. Results: The average AC was 39g of alcohol per week (13g women IL; 64g men, without differences by IL). In women, hazardous AC only increased ALD among those >IL who presented with obesity or MS in combination with T2DM (+36% obesity+MS+T2DM; pIL is likely associated with higher AC and more harmful consumption patterns.