Heliyon (Nov 2023)

Pediatric gliosarcoma, a rare central nervous system tumor in children: Case report and literature review

  • Jinyan Chen,
  • Dong He,
  • Gengyin Guo,
  • Keke Zhang,
  • Wenliang Sheng,
  • Zhen Zhang

Journal volume & issue
Vol. 9, no. 11
p. e21204

Abstract

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Gliosarcoma is a rare and highly malignant central nervous system tumor that accounts for 1%–8% of glioblastomas; it usually occurs in middle-aged and older adults between 40 and 60 years of age and is rare in children. We report an 11-year-old boy with right frontal lobe gliosarcoma who underwent aggressive gross total resection and postoperative radiotherapy, experienced recurrence and subsequently underwent a second operation. To better understand the disease and explore treatment options, we briefly report this case and review the relevant literature.

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