International Journal of General Medicine (Dec 2023)
Factors of Hospital Mortality in Men and Women with ST-Elevation Myocardial Infarction – An Observational, Retrospective, Single Centre Study
Abstract
Martin Marinsek,1,* David Šuran,2,* Andreja Sinkovic1,3,* 1Department of Medical Intensive Care, University Clinical Centre Maribor, Maribor, 2000, Slovenia; 2Department of Cardiology, University Clinical Centre Maribor, Maribor, 2000, Slovenia; 3Medical Faculty of University Maribor, Maribor, 2000, Slovenia*These authors contributed equally to this workCorrespondence: Andreja Sinkovic, Department of medical intensive care, University clinical centre Maribor, Ljubljanska 5, Maribor, 2000, Slovenia, Tel +38641337822, Email [email protected]: There are well-known gender differences in mortality of patients with ST-elevation myocardial infarction (STEMI). Our purpose was to assess factors of hospital mortality separately for men and women with STEMI, which are less well known.Patients and Methods: In 2018– 2019, 485 men and 214 women with STEMI underwent treatment with primary percutaneous coronary intervention (PCI). We retrospectively compared baseline characteristics, treatments and hospital complications between men and women, as well as between nonsurviving and surviving men and women with STEMI.Results: Primary PCI was performed in 94% of men and 91.1% of women with STEMI, respectively. The in-hospital mortality was significantly higher in women than in men (14% vs 8%, p=0.019). Hospital mortality in both genders was associated significantly to older age, heart failure, prior resuscitation, acute kidney injury, to less likely performed and less successful primary PCI and additionally in men to hospital infection and in women to bleeding. In men and women ≥ 65 years, mortality was similar (13.3% vs 17.8%, p = 0.293).Conclusion: Factors of hospital mortality were similar in men and women with STEMI, except bleeding was more likely observed in nonsurviving women and infection in nonsurviving men.Keywords: ST-elevation myocardial infarction, female sex, male sex, sex differences, hospital mortality, 30-day survival, 6-month survival
