Nature Communications (Nov 2018)

A chromosome-scale assembly of the sorghum genome using nanopore sequencing and optical mapping

  • Stéphane Deschamps,
  • Yun Zhang,
  • Victor Llaca,
  • Liang Ye,
  • Abhijit Sanyal,
  • Matthew King,
  • Gregory May,
  • Haining Lin

DOI
https://doi.org/10.1038/s41467-018-07271-1
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Assembly of large, repeat-rich eukaryotic genomes remains challenging. Here, the authors use BioNano Genomics DLS optical mapping and single-molecule nanopore sequencing to generate a chromosome-scale assembly of a new Sorghum bicolor accession and identify variation compared to the publicly available S. bicolor genome.