Nature Communications (Oct 2018)

Defluorosilylation of fluoroarenes and fluoroalkanes

  • Benqiang Cui,
  • Shichong Jia,
  • Etsuko Tokunaga,
  • Norio Shibata

DOI
https://doi.org/10.1038/s41467-018-06830-w
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 8

Abstract

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Transformation of strong C-F bonds into C-Si bonds is an extremely useful strategy for further derivatization of organic molecules. Here, the authors report a nickel-catalyzed strategy to convert aryl fluorides into sylylated arenes while defluorosilylation of alkyl fluorides is achieved under metal-free conditions.