Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans

Joel T. Steyer; Damien J. Downes; Cameron C. Hunter; Pierre A. Migeon; Richard B. Todd

doi:10.1128/mBio.00768-21

mBio (Jun 2021)

Duplication and Functional Divergence of Branched-Chain Amino Acid Biosynthesis Genes in Aspergillus nidulans

Joel T. Steyer,
Damien J. Downes,
Cameron C. Hunter,
Pierre A. Migeon,
Richard B. Todd

Affiliations

Joel T. Steyer: ORCiD; Department of Plant Pathology, Kansas State University, Manhattan, Kansas, USA
Damien J. Downes: ORCiD; Department of Plant Pathology, Kansas State University, Manhattan, Kansas, USA
Cameron C. Hunter: ORCiD; Department of Plant Pathology, Kansas State University, Manhattan, Kansas, USA
Pierre A. Migeon: Department of Plant Pathology, Kansas State University, Manhattan, Kansas, USA
Richard B. Todd: ORCiD; Department of Plant Pathology, Kansas State University, Manhattan, Kansas, USA

DOI: https://doi.org/10.1128/mBio.00768-21
Journal volume & issue: Vol. 12, no. 3

Abstract

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Branched-chain amino acid (BCAA) biosynthesis is important for pathogenic fungi to successfully cause disease in human and plant hosts. The enzymes for their production are absent from humans and, therefore, provide potential antifungal targets.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal