Ethyl 5-methyl-7-(4-morpholinophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate

Hery Suwito; Noorma Kurnyawaty; Kautsar Ul Haq; Abdulloh Abdulloh; Indriani Indriani

doi:10.3390/M998

Molbank (May 2018)

Ethyl 5-methyl-7-(4-morpholinophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate

Hery Suwito,
Noorma Kurnyawaty,
Kautsar Ul Haq,
Abdulloh Abdulloh,
Indriani Indriani

Affiliations

Hery Suwito: Department of Chemistry, Faculty of Science and Technology, Airlangga University, Surabaya 60115, Indonesia
Noorma Kurnyawaty: Department of Chemistry, Faculty of Science and Technology, Airlangga University, Surabaya 60115, Indonesia
Kautsar Ul Haq: Department of Chemistry, Faculty of Science and Technology, Airlangga University, Surabaya 60115, Indonesia
Abdulloh Abdulloh: Department of Chemistry, Faculty of Science and Technology, Airlangga University, Surabaya 60115, Indonesia
Indriani Indriani: Department of Chemistry, Tadulako University, Palu 94118, Indonesia

DOI: https://doi.org/10.3390/M998
Journal volume & issue: Vol. 2018, no. 2
p. M998

Abstract

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A new compound belonging to a dihydrotetrazolopyrimidine derivative, that is, ethyl 5-methyl-7-(4-morpholinophenyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylate, was successfully synthesized using a Biginelli reaction between 4-morpholinobenzaldehyde, ethyl acetoacetate, and 5-aminotetrazole with p-toluenesulfonic acid (pTSA) as a catalyst in ethanol under reflux. The molecular structure of the title compound was characterized on the basis of spectroscopic evidence, using FTIR, HRESI-MS, 1H- and 13C-NMR, and 2D NMR.

Published in Molbank

ISSN: 1422-8599 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Inorganic chemistry
Website: https://www.mdpi.com/journal/molbank

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