A CASE REPORT OF RARE FAMILIAL DEMYELINATING DISEASE

Abstract

Neuromyelitis optica or Devic`s disease is an inflammatory disimmune-neurodegenerative disease characterized by a progressive course, predominantly affecting the optic nerves and spinal cord, with relatively intact brain structures. The differential diagnosis of neuromyelitis optica and multiple sclerosis is based on the identification of a typical clinical and tomographic picture and the presence of a high level of antibodies to aquaporin 4 in the blood serum. We presented a familial clinical case of Devic`s disease in a representative of the indigenous population of Central Asia and the associated difficulties in differential diagnosis. M., 49 years old, was admitted to the Department of Neurology No. 1 of the National Hospital under the Ministry of Health of the Kyrgyz Republic with complaints on decreased vision and a feeling of a “veil” in front of the left eye, blindness on the right, weakness in all limbs, numbness in them, fatigue when walking, dizziness and instability when walking, a feeling of "passing an electric current".Thus, the onset of the disease in a 49-year-old patient was provoked by a hormonal imbalance - after a medical abortion due to a miscarriage, as well as after a viral infection (herpetic), symptoms of brainstem irritation were clinically presented, in particular .

Keywords

• demyelinating disease, neuromyelitis optica, multiple sclerosis, familial case, aquaporin-4