Driving heavy vehicles with dangerous cargo involves various work environments that can significantly impact road safety. This research aims to study the impact of oil and gas tanker drivers’ work environment on driving performance to identify and address any issues that may affect their ability to carry out their jobs effectively. To achieve this, a quantitative approach was employed using a questionnaire survey adapted from the literature review. The data collected from a sample of drivers of oil- and gas-heavy vehicles were analyzed using structural equation modelling. The study’s findings reveal a significant association between the drivers’ work environment and driving performance, represented by a path coefficient of β = 0.237. These results highlight the substantial contribution of the work environment to driving performance, with an effect of 63%. Consequently, the study emphasizes the importance of considering the work environment as a potential factor when assessing and enhancing tanker drivers’ driving abilities during oil and gas transportation.