Practical consensus recommendation on when to do BRCA testing

Abstract

BRCA-mutation associated breast cancer and to future cancer risks and sensitivity to systemic therapies. Now that rapid genetic testing for BRCA1 and BRCA2 mutations is available, BRCA mutation status can be considered when making treatment and prevention decisions for BRCA testing, BRCA mutation carriers with breast cancer. Expert group used data from published literature, practical experience, and opinion of a large group of academic oncologists, to arrive at practical consensus recommendations for use by the community oncologists.

Keywords

• 40 years
• age
• extended germline mutation
• family history
• ovarian cancer
• pancreatic
• paternal history
• prostate