Jichu yixue yu linchuang (Jul 2023)

Progress of specialized pro-resolving mediators in diabetic kidney disease

  • LIU Chong, LIU Yingying, GUO Zhaoan

DOI
https://doi.org/10.16352/j.issn.1001-6325.2023.07.1152
Journal volume & issue
Vol. 43, no. 7
pp. 1152 – 1156

Abstract

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Specialized pro-resolving mediators (SPMs) can promote the regression of chronic inflammatory response in diabetic kidney disease (DKD), inhibit renal fibrosis and protect renal function by inhibiting renal intrinsic cell inflammatory response, antioxidant stress injury and regulate macrophage transformation. With the in-depth study of SPMs, it is expected to become a new target for the treatment of chronic inflammatory diseases such as DKD.

Keywords