Primary vulvar squamous cell carcinomas with high T cell infiltration and active immune signaling are potential candidates for neoadjuvant PD-1/PD-L1 immunotherapy

• Sjoerd H van der Burg,
• Ilina Ehsan,
• Mariette I E van Poelgeest,
• Dana A M Mustafa,
• Helena C van Doorn,
• Kim E Kortekaas,
• Saskia J Santegoets,
• Liselotte Tas,
• Pornpimol Charoentong

Affiliations

Sjoerd H van der Burg

Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, The Netherlands

Ilina Ehsan

Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, The Netherlands

Mariette I E van Poelgeest

Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands

Dana A M Mustafa

Department of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands

Helena C van Doorn

Department of Gynecology, Erasmus Medical Center, Rotterdam, The Netherlands

Kim E Kortekaas

Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands

Saskia J Santegoets

Department of Medical Oncology, Oncode Institute, Leiden University Medical Center, Leiden, The Netherlands

Liselotte Tas

Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands

Pornpimol Charoentong

Department of Medical Oncology and National Center for Tumor Diseases, University Hospital Heidelberg, Applied Tumor Immunity, German Cancer Research Center (DKFZ), Heidelberg, Germany