International Journal of Endocrinology (Jan 2025)

Puerarin Attenuates Podocyte Damage in Mice With Diabetic Kidney Disease by Modulating the AMPK/Nrf2 Pathway

  • Song Xue,
  • Wei Fan,
  • Qingping Li,
  • Hong Huang,
  • Yibo Tang,
  • Min Wu

DOI
https://doi.org/10.1155/ije/4473803
Journal volume & issue
Vol. 2025

Abstract

Read online

Conclusion: Puerarin could attenuate the severity of DKD and protect the podocyte in mice in a dose-dependent way. Also, it might be performed by regulating the AMPK/Nrf2 pathway. These findings may provide a theoretical basis for updating the clinical management of DKD.