Frontiers in Nutrition (Feb 2023)

Prevention and treatment of catheter-related venous thrombosis in long-term parenteral nutrition: A SINuC position statement

  • Vincenzo Zaccone,
  • Luca Santoro,
  • Emanuele Guerrieri,
  • Ilaria Diblasi,
  • Ilaria Roncarati,
  • Giovanna Viticchi,
  • Pietro Vecchiarelli,
  • Angelo Santoliquido,
  • Angelo Santoliquido,
  • Francesca Fiore,
  • Alessio Molfino,
  • Francesco Landi,
  • Francesco Landi,
  • Gianluca Moroncini,
  • Antonio Gasbarrini,
  • Antonio Gasbarrini,
  • Maurizio Muscaritoli,
  • Lorenzo Falsetti

DOI
https://doi.org/10.3389/fnut.2023.1106327
Journal volume & issue
Vol. 10

Abstract

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The implementation of long-term parenteral nutrition (PN) often requires the placement of central venous access, a procedure that carries a considerable risk of catheter-related venous thrombosis (CRT). The occurrence of CRT represents a major event in the natural history of patients in PN since it can lead to central venous access loss and PN failure. Despite the importance of this topic in clinical nutrition, the prevention and treatment of CRT in PN represents one of the “gray areas” of the literature of the presence of few randomized controlled clinical trials and the generally low level of evidence of published scientific papers. Through a narrative review of the literature and a Delphi consensus, the Italian Society of Clinical Nutrition and Metabolism (SINuC) aimed to collect some practical recommendations regarding the current state-of-the-art in the prevention, diagnosis, and treatment of CRT in patients undergoing long-term PN.

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