A Review Article About Digoxin-Herb and Dietary Supplement Interactions

Abstract

Digoxin has a narrow therapeutic index and is the potential drug for interaction with other drugs, herbs and supplements, therefore, regarded to these properties we decided to review the evidence about interaction between herbal-dietary supplements and digoxin. We were collected published articles about this digoxin-herb and supplement interaction for writing a review article. Some the information in this review resulting from, in vitro and animal study that no clinical evidence for them, and others result from clinical evidences. We found fifty herbal products can interact by different mechanism with digoxin and St. John’s wort has the most documented interactions with digoxin.

Keywords

• Digoxin
• Herb
• Interaction