Global Journal of Medicine and Public Health (May 2024)
Clinicopathological study of abnormal uterine bleeding: A two-year study at tertiary care center
Abstract
Background Histopathological assessment of endometrial samples plays a crucial role in the diagnosis of abnormal uterine bleeding (AUB). The present study was conducted to assess histopathology of endometrium with AUB. Methods It is a prospective study conducted in the Department of Pathology, Dr Shankararo Chavan, Government Medical College, Nanded, Maharashtra, India. All cases attending Gynaecology OPD with AUB were included in study. The sample received was Dilatation & Curretage (D&C) samples, endometrial biopsy, polypectomy and hysterectomy specimen. Specimens were routinely processed and stained with Haematoxylin & Eosin stains and microscopic morphological evaluation was done and data recorded and analysed. Results We studied 680 cases. Out of which 661 cases showed significant findings and 19 were reported unsatisfactory samples for evaluation. The commonest histomorphological pattern in these patients were proliferative endometrium 248(36.47%), leiomyoma 100 (14.70%), adenomyosis 90 (13.23%), endometrial hyperplasia 72 (10.58%), secretory endometrium 47(6.91%), atrophic endometrium 40 (6.91%), endometritis 11 (1.61%), endometrial polyp 27(3.97%) , adenomyosis with leiomyoma were seen in 23 cases (3.66%) and least number cases were of endometrial carcinoma forming 3(0.44%) of the total cases taken in the study. Conclusions Histopathological examination of endometrium in patient of AUB shows a wide spectrum of changes ranging from normal endometrium to malignancy. Accurate analysis of endometrial sampling is important in management of AUB.
