Regulation of Cecal Microbiota and Improvement of Blood Lipids Using Walnut Non-Dairy Creamer in High-Fat Mice: Replacing Traditional Non-Dairy Creamer

Mingming Wang; Feng Zhang; Chunlei Tan; Si Huang; Hongyu Mu; Kuan Wu; Yinyan Chen; Jun Sheng; Yang Tian; Ya Wang; Cunchao Zhao

doi:10.3390/molecules29184469

Molecules (Sep 2024)

Regulation of Cecal Microbiota and Improvement of Blood Lipids Using Walnut Non-Dairy Creamer in High-Fat Mice: Replacing Traditional Non-Dairy Creamer

Mingming Wang,
Feng Zhang,
Chunlei Tan,
Si Huang,
Hongyu Mu,
Kuan Wu,
Yinyan Chen,
Jun Sheng,
Yang Tian,
Ya Wang,
Cunchao Zhao

Affiliations

Mingming Wang: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Feng Zhang: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Chunlei Tan: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Si Huang: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Hongyu Mu: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Kuan Wu: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Yinyan Chen: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Jun Sheng: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Yang Tian: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China
Ya Wang: College of Science, Yunnan Agricultural University, Kunming 650201, China
Cunchao Zhao: College of Food Science and Technology, Yunnan Agricultural University, Kunming 650201, China

DOI: https://doi.org/10.3390/molecules29184469
Journal volume & issue: Vol. 29, no. 18
p. 4469

Abstract

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Non-dairy creamer is a class of microencapsulated powdered fats and oils that are widely used in the food industry. However, the oils used in it are hydrogenated vegetable oils, which contain large amounts of saturated fatty acids and are extremely harmful to the human body. This study investigated the effects of replacing hydrogenated vegetable oil with walnut oil to prepare walnut non-dairy creamer on lipid levels and intestinal microorganisms in mice. The results show that low-dose walnut non-dairy creamer significantly decreased the contents of TC and TG in serum and increased the content of HDL-C (p p Firmicutes in the walnut non-dairy creamer group decreased, and the abundance of Bacteroidetes/Firmicutes (B/F) increased, which significantly increased the richness of Lactobacillus and Oscillospira (p Allobaculum richness was significantly decreased (p < 0.01). In conclusion, a low dose of walnut non-dairy creamer can effectively promote the metabolism of blood lipids in vivo, alleviate oxidative stress injury and lipid accumulation damage to mouse hepatocytes, and ameliorate the adverse effects of a high-fat diet on the intestinal microbiota of mice. This study provides a theoretical basis for the replacement of traditional non-dairy creamer and the research and development of walnut deep processing.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

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