Molbank (Jul 2024)

N-(2-(Benzylamino)ethyl)-4-(naphthalene-1-sulfonamido)benzamide

  • Rosalba Leuci,
  • Fulvio Loiodice,
  • Luca Piemontese

DOI
https://doi.org/10.3390/M1856
Journal volume & issue
Vol. 2024, no. 3
p. M1856

Abstract

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In this study, we report the synthesis of N-(2-(benzylamino)ethyl)-4-(naphthalene-1-sulfonamido)benzamide, designed on the basis of the structures of the PPARγ partial agonist SR2067 and of the commercial acetylcholinesterase inhibitor drug donepezil, aiming for a multi-target approach for the therapy of elderly diseases, such as diabetes and Alzheimer’s disease. The compound was fully characterized by using 1H and 13C NMR, FT-IR and HRMS.

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