Federal Research Centre "Information and Management" of the Russian Academy of Sciences; Ivanovo State Medical Academy of the Ministry of Health of the Russian Federation
I Yu Torshin
Federal Research Centre "Information and Management" of the Russian Academy of Sciences
D E Frolova
Ivanovo State Medical Academy of the Ministry of Health of the Russian Federation
N P Lapochkina
Ivanovo State Medical Academy of the Ministry of Health of the Russian Federation
A N Gromov
Federal Research Centre "Information and Management" of the Russian Academy of Sciences
Vitamin D is characterized by undeniable antitumor properties that are important for both prevention and treatment of tumor diseases. The results of a systematic analysis of the molecular mechanisms of antitumor effects of vitamin D (inhibition of the Wnt/b-catenin cascade, the transcription factor WSTF) and the results of clinical studies of patients with estrogen-dependent tumors are presented, indicating the promise of combined use of estrogen and vitamin D.