Frontiers in Oncology (May 2024)

Case report: Axillary lymph node metastases from primary ovarian cancer: a report of two cases and literature review

  • Norlia Abdullah,
  • Nadiah Rosly,
  • Nadiah Rosly,
  • Suria Hayati Md Pauzi,
  • Aida Widure Mustapha,
  • Yulianty Arifuddin,
  • Yulianty Arifuddin

DOI
https://doi.org/10.3389/fonc.2024.1384306
Journal volume & issue
Vol. 14

Abstract

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Ovarian cancer is usually confined intraperitoneally. Distant metastases at presentation is unusual. Its spread via lymphatics is uncommon, and metastasis to axillary lymph nodes is very rare. We report two cases with presentation of axillary lymphadenopathy without breast involvement. Computed tomography scan identified the ovarian masses. Both had elevated Serum Ca 125. The first case had a Grade 2 ovarian endometrioid carcinoma. The second case had a high-grade serous ovarian carcinoma. These cases illustrate the rarity of axillary lymphadenopathy from ovarian cancer. It is important to identify the primary ovarian carcinoma in order to offer appropriate management. Despite surgery and chemotherapy, both succumbed within 3 years from diagnosis.

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