Molecules (Feb 2023)

Recent Advances in the Synthesis of Cyclic Sulfoximines via C–H Bond Activation

  • Bingren Wang,
  • Xiayu Liang,
  • Qingle Zeng

DOI
https://doi.org/10.3390/molecules28031367
Journal volume & issue
Vol. 28, no. 3
p. 1367

Abstract

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Sulfoximines, a ubiquitous class of structural motifs, are widely present in bioactive molecules and functional materials that have received considerable attention from modern organic chemistry, pharmaceutical industries, and materials science. Sulfoximines have proved to be an effective directing group for C–H functionalization which was widely investigated for the synthesis of cyclic sulfoximines. Within the last decade, great progress has been achieved in the synthesis of cyclic sulfoximines. Thus, this review highlights the recent advances in the synthesis of cyclic sulfoximines via the C–H activation strategy and is classified based on the substrate types.

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