Engineered nanoparticle systems: A review on emerging strategies for enhanced cancer therapeutics

Abstract

Over the past decade, the evolution of magnetic nanoparticles as propitious materials in the area of detection of cancer and their treatment was accomplished with magnetic resonance imaging methods and other sensing techniques. In cancer research, the special properties of magnetic nanoparticles are intensively investigated in order to deliver medicines to a specific area via a modified, in vivo, external magnetic field operation. Furthermore, customized anticancer treatment in combination with imaging methods to achieve systematic treatment is discussed. In comparison to previous review articles, this review article provides an overview of compounds composed of metal ions or clusters that are linked to organic ligands to form various dimensional structures, as well as the interaction of tumour cells spreading in the primary site. This research gives a good insight into cutting-edge research on a variety of tumor-related topics, such as the clonal evolution theory, the use of magnetic nanoparticles in cancer diagnosis, treatment, targeted drug delivery agents, and metal organic frameworks for treating cancers as well as future developments in the field of oncology.

Keywords

• Magnetic nanoparticles
• Cancer treatment
• Clonal evolution theory
• Metal organic frameworks
• Targeted drug delivery