Evaluation of mean platelet volume and platelet count in patients with hidradenitis suppurativa

Abstract

Background and Design: Hidradenitis suppurativa (HS) is a chronic inflammatory condition of the apocrine glands. The mean platelet volume (MPV) is a risk factor for many inflammatory diseases and can be used as a marker of inflammatory response. This study aimed to evaluate the MPV and platelet count in patients with HS and compare them with those of healthy controls. Materials and Methods: Between September 2014 and October 2019, 97 patients diagnosed with HS and 78 healthy controls were included. Their MPVs and platelet counts were compared retrospectively. Results: The MPV was 10.17±0.94 in the patient group and 9.53±0.63 in the control group, with the difference being significant (p<0.05). No significant difference was noted between the groups in terms of platelet values. Conclusion: The MPV was significantly higher in patients with HS than in healthy controls. Based on this finding, the MPV may be used as an inflammatory marker in this patient group.

Keywords

• hidradenitis suppurativa
• mean platelet volume
• inflammatory markers
• platelet parameters